There Is Hope
for Knee Pain
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  1. Herminia
    "I Failed PT, Steroid Shots, Rooster Shots, and Last They Told Me Knee Surgery, Now After Ozone Shots With Dr. Seda I Am Dancing Again" Herminia Castaneda, San Antonio, TX
  2. San Antonio
    Jesse N Valerie Baca recommends Dr. Seda. December 30, 2019 at 12:10 PM · I definitely recommend people that are in pain to go see Dr.Seda. My husband has seen many Doctors and nothing they did helped his knee pain they all said surgery was the only solution. We can't afford the surgery or for him to be out of work. Dr.Seda and his treatment helped my husband. He can walk with no pain.
  3. Fidencio
    Edward Soto recommends Dr. Seda. December 18, 2019 at 9:50 AM · I have walked out of Dr Ceda’s office wanting to shed tears of joy and back and knee pain have been brought to a 2 on a 1-10 scale...very unexplainable at how you can literally walk out almost a new person if you have lived in pain for years..thank you Dr. Ceda..May God bless you and you practice always!
Comparison between intra-articular ozone and placebo in the treatment of knee osteoarthritis: A randomized, double-blinded, placebo-controlled study.


The aim of the trial was to determine the effectiveness of oxygen-ozone injections on knee osteoarthritis concerning pain reduction, joint functional improvement, and quality of life.

In this randomized, double-blinded, placebo-controlled clinical trial, 98 patients with symptomatic knee osteoarthritis (OA) were randomized into two groups receiving intra-articular 20 μg/ml of ozone (OZ) or placebo (PBO) for 8 weeks. The efficacy outcomes for knee OA were the Visual Analogue Scale (VAS), Lequesne Index, Timed Up and Go Test (TUG Test), SF-36, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Geriatric Pain Measure (GPM).

After 8 weeks of treatment, ozone was more effective than the placebo: VAS [mean difference (MD) = 2.16, p < 0.003 (CI 95% 0.42-3.89)], GPM [MD = 18.94, p < 0.004 (CI 95% 3.43-34.44)], LEQ [MD = 4.05, p < 0.001 (CI 95% 1.10-7.00)], WOMAC (P) [median of diff = 9.999, p = 0.019 (CI 95% 0.000-15.000)], WOMAC (JS) [median of diff = 12.499, p < 0.001 (CI 95% 0.000-12.500)], WOMAC (PF) = [median of diff = 11.760, p = 0.003 (CI 95% 4.409-19.119)], TUG (no statistical difference) and SF-36 (FC) [(MD = -25.82, p < 0.001 (CI 95% 33.65-17.99)], SF-36 (PH) [MD = -40.82, p < 0.001 (CI 95% -54.48-27.17)], SF-36 (GSH) [MD = -3.38, p < 0.001 (CI 95% -4.83-1.93)], SF-36 (SA) [MD = 2.17, p < 0.001 (CI 95% -19.67-8.24), SF-36 (EA) [MD = -35.37, p < 0.001 (CI 95% -48.86-21.89)]. Adverse events occurred in 3 patients (2 in the placebo group and 1 in the ozone group) and included only puncture accidents.

The study confirms the efficacy of ozone concerning pain relief, functional improvement, and quality of life in patients with knee osteoarthritis.



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